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How Depression Alters Stress, Health, and Lifespan

Neuroscience News - 16 Nov 2024 21:44
How Depression Alters Stress, Health, and Lifespan Depression disrupts the body's stress systems, causing physical health risks like heart disease, diabetes, and stroke, and reducing life expectancy by 7-10 years. The condition triggers brain structure changes, such as a 40% reduction in subgenual prefrontal cortex volume, and disrupts hormone systems involving CRH, norepinephrine, and cortisol.
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